I will examine by observing and looking around! Discovery, visualization, diagnosis, treatment.
Keywords: biosensor, live imaging, drug delivery, nanocapsule, theranostics, luminescence
We aim to non-invasively visualize the functions and dysfunctions of biological entities for disease diagnosis, toxicity testing, and active ingredient screening. Utilizing live cell imaging and flow cytometry for high-speed analysis, we are developing an analytical system comparable to animal experiments. We create non-invasive sensor molecules that detect chemical reactions and physical interactions occurring in vivo, introduce them into cells, expose them to harmful or effective substances, and detect the sensor's response using light (fluorescence). We are establishing testing methods for the toxicity of anticancer drugs, air pollutants, and the efficacy of quasi-drugs. On the other hand, we are also advancing the production of nanocapsules composed of disease-targeting sensor molecules. All production is conducted under physiological conditions, aiming for a cocktail delivery system that combines conventional synthetic pharmaceuticals and biopharmaceuticals. The sensor molecules are used to monitor the delivery situation. Furthermore, we are also working on constructing an external discharge system for harmful substances accumulated in the body due to metabolic disorders and a discharge system.
- Company：埼玉大学 オープンイノベーションセンター
- Price：Other
